Generating Antibiotics Incentives Now (GAIN) Act

On July 9th, 2012, President Barack Obama signed into law the Food and Drug Administration Safety and Innovation Act and with it the Generating Antibiotics Incentives Now (GAIN) Act, which includes provisions to incentivize research and development of antibiotics. The Hartford Courant – citing Dr. Jeffrey Townsend, a professor in the Department of Ecology and Evolutionary Biology at Yale, described the GAIN Act as “brilliant.” In June of 2012, described GAIN as “…a Holy Cow provision.” Because of the dearth of antibiotics coming to market to treat a growing list of antibiotic-resistant infections, the antibiotic pipeline is running dry and, in turn, placing the public health at risk. Through the GAIN Act, Congress has addressed the issue of antibiotic resistance at a critical juncture: according to CDC data, more than 1.7 million people acquire bacterial infections in U.S. hospitals each year — and 99,000 people die as a result of these bacterial infections, of which up to 70 percent are resistant to at least one drug.

Title VIII - Generating Antibiotic Incentives Now (GAIN)

Incentives are provided under Title VIII of the new Generating Antibiotic Incentives Now (GAIN) statute, which received strong bipartisan support in Congress and was signed into law by President Obama in July 2012.Download


Antimicrobial Resistance: An Epic Story of Burden and Progress.

tatfarOne year in, the GAIN Act spurs innovation in antibiotic development. See it here


Transatlantic Taskforce on Antimicrobial Resistance

tatfarThe full report can be found here


List of GAIN supporters